DHEA-S • Code

  • Test Type
  • Specimen Information
Test Description

Dehydroepiandrosterone sulfate is produced by the addition of a sulfate group, catalyzed by the sulfotransferase enzymes SULT1A1 and SULT1E1, which also produce estrone sulfate from estrone. DHEA sulfate can also be back-converted to DHEA through the action of steroid sulfatase.

When should this test be ordered?
A DHEA-S test may be ordered, along with other hormone tests, whenever excess (or, more rarely, deficient) androgen production is suspected and/or when a health practitioner wants to evaluate a person's adrenal gland function.
High Risk · Outside Reference Range
Lower than reference range:

Male::
(0-364) days : <= 3.3 (µg/dL)
(365-1824) days : <= 0.4 (µg/dL)
(1825-3649) days : <= 2.7 (µg/dL)
(3650-5474) days : <= 24.3 (µg/dL)
(5475-7299) days : <= 70.1 (µg/dL)
(7300-9124) days : <= 210.9 (µg/dL)
(9125-12774) days : <= 159.9 (µg/dL)
(12775-16424) days : <= 88.8 (µg/dL)
(16425-20074) days : <= 44.2 (µg/dL)
(20075-23724) days : <= 51.6 (µg/dL)
(23725-27374) days : <= 33.5 (µg/dL)
(>= 27375) days : <= 16.1 (µg/dL)

Female::
(0-364) days : <= 3.3 (µg/dL)
(365-1824) days : <= 0.4 (µg/dL)
(1825-3649) days : <= 2.7 (µg/dL)
(3650-5474) days : <= 33.8 (µg/dL)
(5475-7299) days : <= 65 (µg/dL)
(7300-9124) days : <= 147.9 (µg/dL)
(9125-12774) days : <= 98.7 (µg/dL)
(12775-16424) days : <= 60.8 (µg/dL)
(16425-20074) days : <= 35.3 (µg/dL)
(20075-23724) days : <= 18.8 (µg/dL)
(23725-27374) days : <= 9.3 (µg/dL)
(>= 27375) days : <= 11.9 (µg/dL)

Greater than reference range:

Male::
(0-364) days : >= 607.1 (µg/dL)
(365-1824) days : >= 19.5 (µg/dL)
(1825-3649) days : >= 85.3 (µg/dL)
(3650-5474) days : >= 247.1 (µg/dL)
(5475-7299) days : >= 492.1 (µg/dL)
(7300-9124) days : >= 492.1 (µg/dL)
(9125-12774) days : >= 449.1 (µg/dL)
(12775-16424) days : >= 427.1 (µg/dL)
(16425-20074) days : >= 331.1 (µg/dL)
(20075-23724) days : >= 295.1 (µg/dL)
(23725-27374) days : >= 249.1 (µg/dL)
(>= 27375) days : >= 123.1 (µg/dL)

Female::
(0-364) days : >= 607.1 (µg/dL)
(365-1824) days : >= 19.5 (µg/dL)
(1825-3649) days : >= 85.3 (µg/dL)
(3650-5474) days : >= 280.1 (µg/dL)
(5475-7299) days : >= 368.1 (µg/dL)
(7300-9124) days : >= 407.1 (µg/dL)
(9125-12774) days : >= 340.1 (µg/dL)
(12775-16424) days : >= 337.1 (µg/dL)
(16425-20074) days : >= 256.1 (µg/dL)
(20075-23724) days : >= 205.1 (µg/dL)
(23725-27374) days : >= 246.1 (µg/dL)
(>= 27375) days : >= 154.1 (µg/dL)
Borderline Risk ·
Not applicable for this test.
Low Risk · Within Reference Range
Reference Range:

Male::
(0-364) days : 3.4-607 (µg/dL)
(365-1824) days : 0.5-19.4 (µg/dL)
(1825-3649) days : 2.8-85.2 (µg/dL)
(3650-5474) days : 24.4-247 (µg/dL)
(5475-7299) days : 70.2-492 (µg/dL)
(7300-9124) days : 211-492 (µg/dL)
(9125-12774) days : 160-449 (µg/dL)
(12775-16424) days : 88.9-427 (µg/dL)
(16425-20074) days : 44.3-331 (µg/dL)
(20075-23724) days : 51.7-295 (µg/dL)
(23725-27374) days : 33.6-249 (µg/dL)
(>= 27375) days : 16.2-123 (µg/dL)

Female::
(0-364) days : 3.4-607 (µg/dL)
(365-1824) days : 0.5-19.4 (µg/dL)
(1825-3649) days : 2.8-85.2 (µg/dL)
(3650-5474) days : 33.9-280 (µg/dL)
(5475-7299) days : 65.1-368 (µg/dL)
(7300-9124) days : 148-407 (µg/dL)
(9125-12774) days : 98.8-340 (µg/dL)
(12775-16424) days : 60.9-337 (µg/dL)
(16425-20074) days : 35.4-256 (µg/dL)
(20075-23724) days : 18.9-205 (µg/dL)
(23725-27374) days : 9.4-246 (µg/dL)
(>= 27375) days : 12-154 (µg/dL)
Testing Method Used
Electrochemiluminescence Immunoassay.

Sample is stable for 2 days at 2-8°C.

Please ship samples daily.
Improvements and Prevention
Specimen Type
Serum
Fasting Required
No, but may be done with other tests that requires fasting.
Drawing and Processing
  1. Draw from a vein into a SST tubetube1
  2. Invert tube (do not shake) 1-2 times to mix adequately
  3. Let stand upright in tube rack for 30 minutes
  4. Centrifuge for 15 minutes at 3300rpm
  5. Do not leave at room temperature for more than 1 hour
  6. Keep cold in a refrigerator to maintain stability, until ready to ship
Shipping Instructions
  1. Freeze ice packs 24 hours prior to use
  2. Place ice packs inside the Styrofoam insulated kit
  3. Place processed tubes inside biohazard bag, place inside kit
  4. Seal box, print airbill and adhere to box and wait for courier to pick up
Rejection Criteria
QNS; temperature out of range upon receipt; grossly hemolyzed or lipemic; wrong specimen type; sample stability exceeded for this analyte; unlabeled or mislabeled specimen.
References

The information provided here is intended for educational purposes only and should not be used or substituted as medical advice. You should consult a healthcare practitioner regarding medical diagnosis or treatment.