Test Description

Adipokines contribute to the pathophysiology of obesity-linked disorders through their ability to modulate inflammatory and metabolic processes. Adiponectin is secreted by fat tissue. It is associated with pathogenesis of type 2 diabetes, hypertension and cardiovascular disease.

When should this test be ordered?
Monitoring helps with medical weight loss management programs. Levels are significantly reduced in obese subjects and in diabetics compared to non-diabetics. Weight reduction significantly increases circulating levels. Appropriate testing includes evaluation of insulin resistance and diabetes as well as lipid and abnormalities of glucose metabolism.
High Risk · <= 2.2 (ug/mL) & >= 24.3 (ug/mL)
There may be some evidence of insulin resistance. Consider losing excess weight, eating a healthy diet that is high in fiber and restricted in carbohydrates and getting regular amounts of exercise.
Borderline Risk ·
There may be some evidence of insulin resistance. Consider losing excess weight, eating a healthy diet that is high in fiber and restricted in carbohydrates and getting regular amounts of exercise.
Low Risk · 2.3-24.2 (ug/mL)
Within reference range.
Testing Method Used
Latex enhanced Immunoturbidimetric method.

Sample is stable for 8 days at 2-8°C.

Please ship samples daily.
Improvements and Prevention
Weight loss will elevate abnormally low levels and thus reduce the damaging effects of adiponectin on the metabolic system, heart and kidneys. Reducing inflammation may contribute to lowering elevations above the normal range.
Specimen Type
Serum
Fasting Required
No, but may be done with other tests that requires fasting.
Drawing and Processing
  1. Draw from a vein into a SST tubetube1
  2. Invert tube (do not shake) 1-2 times to mix adequately
  3. Let stand upright in tube rack for 30 minutes
  4. Centrifuge for 15 minutes at 3300rpm
  5. Do not leave at room temperature for more than 1 hour
  6. Keep cold in a refrigerator to maintain stability, until ready to ship
Shipping Instructions
  1. Freeze ice packs 24 hours prior to use
  2. Place ice packs inside the Styrofoam insulated kit
  3. Place processed tubes inside biohazard bag, place inside kit
  4. Seal box, print airbill and adhere to box and wait for courier to pick up
Rejection Criteria
QNS; temperature out of range upon receipt; grossly lipemic or hemolyzed; wrong specimen type; sample stability exceeded for this analyte; unlabeled or mislabeled specimen.
References

The information provided here is intended for educational purposes only and should not be used or substituted as medical advice. You should consult a healthcare practitioner regarding medical diagnosis or treatment.

* Vibrant™ Tests have been developed and its performance characteristics determined by the CLIA-certified laboratory performing the test. This test has not been cleared or approved by the U.S. Food and Drug Administration (FDA). Although FDA does not currently clear or approve laboratory-developed tests in the U.S., certification of the laboratory is required under CLIA to ensure the quality and validity of the tests.